[1] Megadictyon is a large lobopodian, with a body length (excluding appendages) possibly up to 20 centimeters in total.

[2] The head has a pair of robust frontal appendages[3] associated with rows of spines and terminal claws.

[2] Located on the underside of the head is a radiodont-like mouthpart formed by multiple layers of plates and tooth-like structures.

Only 8 segment/limb pairs are countable in the incomplete fossil materials which are lacking the posterior region, so it may have had more (possibly up to 11 to 13) in nature.

[5] Aysheaia Onychodictyon Tardigrada Onychophora Megadictyon Jianshanopodia Hadranax Kerygmachela Pambdelurion Utaurora Opabinia Aegirocassis Peytoia Schinderhannes bartelsi Cambroraster Hurdia Amplectobelua Lyrarapax Anomalocaris Houcaris Deuteropoda