[2] Twohey's reports have exposed exploitative doctors, revealed untested rape kits, and uncovered a secret underground network of abandoned unwanted adopted children.

[5] The story led to Weinstein's firing and helped to ignite the viral #MeToo movement started by the American activist Tarana Burke.

[10] She reported for Reuters before joining The New York Times in 2016, first focusing on Donald Trump's tax history, possible business ties to Russia, and his past treatment of women.

[13][14] From 2010 to 2011, Twohey published a series of articles in the Chicago Tribune detailing cases of doctors who had been convicted of violent felonies or sex crimes and were still practicing and abusing patients.

[16][17] In 2013, Twohey published an investigative report in Reuters News that detailed how some people in the United States were using the internet to find places to abandon their adopted children.

[34] In December 2021, Twohey and Gabriel Dance published an investigative report in The New York Times about an American web forum dedicated to discussing and encouraging suicide.

[36] In November 2022, The New York Times published a piece co-written by Twohey about the concerns some medical professionals (including Hilary Cass) had about the possible consequences of transgender adolescents taking puberty blockers.

[38] Erin Rook of LGBTQ Nation called the reporting "reckless" and provided the perspectives of three health experts who disputed the analysis, including one who was interviewed for the New York Times article.

[39] Eckert also wrote an article published by Science-Based Medicine, in which he said "the reporting ignored evidence and important context to weave a narrative portraying puberty blockers as far more risky than they actually are".

[41] On social media, lawyer and transgender rights activist Chase Strangio of the ACLU pointed to the piece as an example of how "rhetoric found in major news outlets fuels anti-trans violence", according to the geek culture website The Mary Sue.

[43] Fox News said the report "sparked jeers from critics on social media mocking their newfound nuanced coverage of puberty blockers" and was "also blasted by progressives".

[49] Megan's mother Mary Jane Twohey worked as a Congressional aide and as a news producer at WETA-TV in Washington, D.C. before serving for many years as a spokesperson and media-relations manager for Northwestern University in Evanston, Illinois.