In the early 19th century, he was known to row out to meet ships from London, Liverpool, Havre, and New York City to get the news earlier than other Charleston papers.

[2] Its editor, Thomas R. Waring Jr., was a staunch segregationist, as was staffer W. D. Workman Jr., who ran for public office in a campaign that united South Carolina's formerly divided racial and economic conservatives.

It has taken a leadership role in exposing corruption and reducing local news deserts with its Uncovered project, a partnership with more than 18 South Carolina newspapers.

In 2019, Tony Bartelme won the inaugural Victor K. McElheny Knight Science Journalism Award for a story about climate change and the Gulf Stream.

In 2018, the newspaper won the American Society of News Editors Deborah Howell Award for a story about the demise of the Piggly Wiggly Carolina grocery chain.

[6] In 2008, Reporter Tony Bartelme also won the prestigious Gerald Loeb Award for a story about the effect of China's growth on local economies.

[7] The reported numbers for The Post and Courier's circulation as of the six months ended September 30, 2009, were 86,084 daily and 94,940 on Sundays.

A decline in revenue made the paper offer a buyout to employees in 2008 in an attempt to streamline the company and save money.

One addition to the paper is the weekly Charleston Scene guide—published on a Thursday, containing entertainment, music and food reviews for the local area.