In this film, Khesari Lal Yadav and Sahar Afsha are in lead roles, while Ritu Singh, Amit Shukla, Shraddha Nawal, Surya Dwivedi, Uday Tiwari, Mahesh Acharya, Neel Kamal Singh, Manoj Tiger, Brijesh Tripathi and others in supporting roles.

Amrapali Dubey make special appearance in song "Laga Ke Vaseline".

[3] Telugu actress Sahar Afsha make her Bhojpuri debut with this film.

[6] Music of Mehandi Laga Ke Rakhna 3 is composed by Rajnish Mishra with lyrics written by Vinay Bihari, Pyare Lal Yadav, Manoj Bhagat, Ajit Halchal and Yadav Raj.

[7][8] First song of this film "Hothwa Se Madhu Chuye" was released on 20 February 2020 on official YouTube channel.