Plant species found in the sanctuary include Coptis teeta Taxus baccata, Terminalia myriocarpa, Terminalia bellirica, Terminalia chebula, Altingia excelsa, Jalauma phellocarpa, Abizzia lucida, Abizzia procera, Abizzia arunachalensis, Abizzia sherriffi, Acacia caesia, Canarium strictum, Lagerstroemia speciosa, Duabanga grandiflora, Michelia champaca, Messua ferra, Dillenia indica, Castanopsis indica, Bischofia javanica, Magnolia species, Ailanthus grandis, Kydia calycina, Bombax ceiba, Schima wallichii, Ficus altissima, Ainus nepalensis, Populus amblei, Castanopsis indica, Castanopsis spicata, Quercus griffithi, Quercus amellosa, and Betula alnoides.

The animals found in the sanctuary include tiger, leopard, clouded leopard, Asian elephant, gaur, sloth bear, barking deer, marbled cat, capped langur, slender loris, white browed gibbon, musk deer, Mishmi takin, red panda, and serow.

[citation needed] The sanctuary harbours a rich lichen diversity, with 177 species belonging to 71 genera and 35 families identified across its altitudinal range (400–2700 m).

The mid-altitude range of 1400–1600 m showed peak lichen diversity, displaying a unimodal pattern in relation to altitude.

Humidity and altitude were identified as key factors influencing lichen distribution and diversity patterns within the sanctuary.