Mekanism is a San Francisco-based creative agency that specializes in the development and production of marketing campaigns, commercials and branded entertainment for multinational companies.

[3] In 2003 Means spun off the company as an independent fully integrated creative production studio to develop branded content outside traditional television commercial channels.

[5] During this period, the agency began to develop its reputation for reaching younger audiences and telling branded stories in off-beat ways that tended to go viral.

[10][1][6] The agency has completed campaigns for such companies as Microsoft, Nike, Axe, Frito-Lay, PepsiCo, Nordstrom, Google, Muscle Milk, and GE.

[8] In 2012, Mekanism launched a campaign for the American Society for the Prevention of Cruelty to Animals with Dan Harris from ABC’s Nightline featuring Harris's adopted cat, "Hovercat"; the video went viral and garnered over 1 million views, with Brendan Gahan, Mekanism's Director of Social Media, noting, "The internet loves cats and it was done for a good cause so it's great to see people rally around it.

[18] Mekanism also became the Agency of Record for Method Home, Muscle Milk, Pepsi, Brisk Ice Tea, Amp Energy Drink, Art.com, and Virgin Mobile.

On October 31, 2022, Eleven, whose brands included CommonSpirit Health, Pella and Kraken, became part of Mekanism, planning to move into the company's San Francisco facilities.

[20] In May 2010, the business magazine Fast Company published a profile of Mekanism, during which Harris claimed that the firm could "guarantee [they] can create an online campaign and make it go viral."