She then joined August Böck's laboratory as a doctoral student and in 2004, graduated with her PhD awarded summa cum laude on "[NiFe]-Hydrogenases of Escherichia coli: Functions of Proteins involved in Metal Center Assembly".

[8] They found the pilous fraction of the DNA-uptake machinery also enables the adherence to chitinous surfaces, such as exoskeleton of arthropods, also under conditions of water currents.

[13] They started also working on the HGT capabilities of Acinetobacter baumannii, another human pathogen, known for frequently being resistant to a variety of antibiotics, and mostly associated with high infection rates in hospital settings.

[15][16] The research of Blokesch and her group has been featured in international news outlets such as La Razón,[17] Radio Télévision Suisse,[18] The Times of India,[19] National Geographic Magazine[20] and Deutschlandfunk.

[23] In 2017, she was selected among 25 life changing women ("25 Frauen, deren Erfindungen unser Leben verändern") by four German news outlets (Edition F, ZEIT online, Handelsblatt and Gründerszene).