[1] She wrote her thesis on "Mercuric ion reductase: mutagenesis of n- and c-terminal paired cysteines and initial crystallization studies".
[3] As a Helen Hay Whitney postdoctoral fellow under the supervision of Phillip Allen Sharp, she invented technology to join long RNA molecules,[4] and published a seminal paper establishing the chemical mechanism of pre-mRNA splicing.
[7][8] At Brandeis, Moore established her own laboratory in the Biochemistry Department to research pre-mRNA splicing and its connections to intracellular mRNA localization, translation, and degradation.
In 2007, Moore moved her research group to the Biochemistry and Molecular Pharmacology Department at the University of Massachusetts Chan Medical School (UMass Med).
That year, Moore and her collaborator Ananth Karumanchi, also received a Bill and Melinda Gates Foundation Grand Challenges grant for their project "siRNA-based Therapeutics for Preeclampsia.