Melissa Mazzotta (born 21 June 1972) is a former professional tennis player from Venezuela.

She was a two-time All-American collegiate tennis player at the University of Miami.

[1] As a professional player, she reached a top singles ranking of 182 in the world.

Her WTA Tour career included a win over Rachel McQuillan in Los Angeles in 1994 and she was a doubles runner-up at Bogota in 1998.

She appeared in a total of six Fed Cup ties for her native Venezuela, two in 1991 and four in 1996.