Melero-Moose developed a style of abstract, mixed-media paintings that reference the landscape and culture of her Northern Paiute people.
She painted with acrylic washes with layers rice paper and natural objects, such as willow, tule, cattails, and pine nuts.
[1] Beginning in 2018, the Nevada Museum of Art gave Melero-Moose a fellowship to research and create a directory and archive of Great Basin Native artists.
[8] In 2015, the School for Advanced Research chose Melero-Moose as its Ronald and Susan Dubin fellow.
[5] The Nevada Museum of Art in Reno named her the inaugural Peter E. Pool Research Fellow in 2018.