Melissa Middleton (born June 6, 1982) is an American former professional tennis player.

Middleton, a right-handed player, was born and raised in Houston, Texas.

[1] A successful player in junior tennis, she won both the Easter Bowl and USTA National Clay Court Championships as an under 16 in 1996.

[2] On the professional tour, Middleton reached a career best singles ranking of 225.

[3] As a doubles player she made it to 116 in the world and was a WTA Tour finalist in Memphis in 2002.