She is best known for playing Bernadette Rostenkowski-Wolowitz on the CBS sitcom The Big Bang Theory from 2009 to 2019, for which she was nominated for the Critics Choice Television Award in 2013.

Rauch also had supporting roles in I Love You, Man (2009), Ice Age: Collision Course and Flock of Dudes (both 2016), and Ode to Joy and The Laundromat (both 2019).

[6] Rauch earned a Bachelor of Fine Arts in acting and graduated from Marymount Manhattan College in New York City in 2002.

In December 2011, Rauch and fellow cast members of The Big Bang Theory received the first of four nominations for the Screen Actors Guild Award for Outstanding Performance by an Ensemble in a Comedy Series.

[10][11][12][13] Other acting credits include True Blood (in which she had a recurring role in 2010 as Summer, a girl who likes Hoyt), The Office, the American remake of the Australian TV series Kath & Kim, Wright v Wrong, and the film I Love You, Man.

Rauch is also part of the comedic stage show The Realest Real Housewives cast with Casey Wilson, June Diane Raphael, Jessica St. Clair and Danielle Schneider.

Rauch is married to writer Winston Beigel, who collaborated with her on The Miss Education of Jenna Bush and other projects.