He was named to the SAL All-Star Game, and participated in the league's Home Run Derby that year.

[6] Mesa made his major league debut on September 22, 2012, against the Oakland Athletics in the bottom of the 14th inning as a pinch runner with the score tied 9–9.

[7] He recorded his first major league hit, an RBI single, on October 1 against Boston Red Sox pitcher Andrew Bailey.

[9] Mesa signed a minor league deal with the Kansas City Royals on December 28, 2013, and played 23 games for the Triple-A Omaha Storm Chasers.

[10] Mesa was assigned to the Double-A New Hampshire Fisher Cats on May 27, then sent to the Triple-A Buffalo Bisons on June 12.

[13] Mesa split the 2016 campaign between New Hampshire and Buffalo, accumulating a .241/.299/.372 batting line with five home runs, 22 RBI, and five stolen bases across 69 games.