Mellette is a city in Spink County, South Dakota, United States.

[7] According to the United States Census Bureau, the city has a total area of 0.26 square miles (0.67 km2), all land.

[8] Northwestern Area School District #56-7 is located in the city of Mellette.

Northwestern serves northern Spink County, and has a K-12 enrollment of 260 students.

Northwestern Wildcat athletics participates under the SDHSAA Class B, and has a combined total of 15 state titles.

The racial makeup of the city was 97.1% White, 0.5% Native American, and 2.4% from two or more races.

About 10.9% of families and 12.6% of the population were below the poverty line, including 9.9% of those under the age of eighteen and 28.6% of those 65 or over.