Melrose is a village in Jackson County, Wisconsin, United States.

There were 250 housing units at an average density of 308.6 per square mile (119.2/km2).

27.8% of all households were made up of individuals, and 16% had someone living alone who was 65 years of age or older.

There were 229 housing units at an average density of 290.1 per square mile (111.9/km2).

The racial makeup of the village was 99.05% White, 0.19% Pacific Islander, and 0.76% from two or more races.

30.7% of all households were made up of individuals, and 19.7% had someone living alone who was 65 years of age or older.

None of the families and 3.4% of the population were living below the poverty line, including no under eighteens and 11.7% of those over 64.