Melville is a town in St. Landry Parish, Louisiana, United States.

It is directly across the river from the ghost town Red Cross, Louisiana.

The racial makeup of the town was 51.9% Black, 45.0% White, 0.2% Native American, 0.2% Asian and 1.0% from two or more races.

The racial makeup of the town was 52.47% White, 45.78% African American, 0.87% Asian, and 0.87% from two or more races.

In 2010, Melville had the 12th-lowest median household income of all places in the United States with a population over 1,000.