Melville is an affluent hamlet and census-designated place (CDP) in the Town of Huntington in Suffolk County, on Long Island, in New York, United States.

[11][12] In the 1950s, Melville and three of its neighbors, Dix Hills, Wyandanch, and the area known as Sweet Hollow, proposed incorporating as a single village.

[13][15] In 2001, Melville, Dix Hills, Wheatley Heights, and East Farmingdale, which are all within the same school district, proposed incorporating as a single village.

Melville and Hauppauge are the two primary business centers of Suffolk County, which is home to almost approximately 1.5 million people.

Melville is home to the U.S. headquarters for several national and international corporations, including Canon USA,[21][22] Chyron Corporation, Leviton, MSC Industrial Direct, Nikon USA, the medical and dental supply distributor Henry Schein, Bouchard Transportation, and Verint Systems.

In early 2013, Canon Inc. moved into its new regional headquarters for North and South America to Melville, building a $500-million 668,296-square-foot (62,086.7 m2) glass structure near Exit 49 of the Long Island Expressway on the 52-acre (210,000 m2) site of a former pumpkin farm.

[21] Companies once headquartered in Melville that subsequently relocated include OSI Pharmaceuticals, which was bought by Astellas Pharma of Japan, Allion Healthcare, which was acquired by a private equity firm, Hain Celestial, which moved to Lake Success in Nassau County, Arrow Electronics, which relocated to Centennial, Colorado in 2011, global staffing giant Adecco Staffing, USA, which in 2014 moved their U.S. headquarters to Jacksonville, Florida, and Gentiva Health Services, a Fortune 1000 provider of health services, which relocated to Atlanta in 2006.

Other firms to leave include First Data, Olympus America Inc., the U.S. subsidiary of Olympus Corporation, who moved in 2006 to Center Valley, Pennsylvania, and the national pizza chain Sbarro, which declared bankruptcy and reemerged in 2014, relocating to Columbus, Ohio.

[23] Around 2002, Swiss International Air Lines's North American headquarters moved from Melville to Uniondale.

[24][25] The building is now owned by Damianos Realty Group, LLC, a Long Island-based real estate company.

Katharine Gibbs School – Melville serves the post-school population with certificates and associate degrees.

The independent television station WLNY-TV operates a studio in Melville, where it had been based prior to being acquired by CBS and moving to the network's Manhattan facility.

Until 1927, Melville was served by the Huntington Railroad's streetcar line, which ran along what today is NY Route 110 and has now been replaced by the S1 bus.

[27] The "Suffolk Clipper" express bus service also serves the numerous business parks in South Melville during weekdays.