EIC voyage #1 (1787–1788): Captain Philip Dundas sailed from The Downs on 6 January 1787, bound for Bombay and China.

Homeward bound, she crossed the Second Bar on 11 January 1788, reached St Helena on 17 April, and arrived at The Downs on 24 June.

[4] EIC voyage #3 (1792–1793): Captain Dundas sailed from The Downs on 8 March 1792, bound for Madras and Bengal.

Melville Castle was at Johanna on 17 June, reached Madras on 21 July, and arrived at Diamond Harbour on 15 August.

[1] Captain John Alexander Haldane: War with France had broken out while Melville Castle was returning from her third voyage.

[2] However, the British government was contemplating an invasion of Île de France (Mauritius), and detained a large number of East Indiamen in England to serve as transports.

Fortunately, he was able to find a replacement who was both acceptable to the EIC and as was the practice at the time, who could afford to purchase the command from Haldane.

[6] EIC voyage #4 (1794–1795): It was Captain John Lambe who sailed Melville Castle from Portsmouth on 2 May 1794, bound for Madras and Bengal.

Melville Castle reached Rio de Janeiro on 6 July and arrived at Bombay on 30 September.

[1] The "United Company of Merchants of England trading to the East Indies" offered 28,966 bags of rice for sale on 25 March.

She was repaired and the Government of the Batavian Republic chartered her to carry troops to the Cape of Good Hope and Batavia, Dutch East Indies.