Melvin Malcolm Grumbach (December 21, 1925 – October 4, 2016) was an American pediatrician and academic who specialized in pediatric endocrinology.

Called Edward B. Shaw Distinguished Professor of Pediatrics, Emeritus at the University of California, San Francisco School of Medicine, Grumbach was noted for his research and writing on the effect of hormones and the central nervous system on growth and puberty and their disorders; the function of the human sex chromosomes; and disorders of sexual development.

During the Korean War he served as a captain in the United States Air Force Medical Corps, with assignments at Oak Ridge Institute of Nuclear Studies in Tennessee and at Fort Detrick Biological Laboratories in Maryland.

Grumbach stepped down as chairman of pediatrics in 1986 and retired in 1994, but he remained active in the field until December 2014.

[1][2] Grumbach made many seminal contributions the understanding of pediatric endocrinology including extensive studies on the development and function of the endocrine and neuroendocrine systems from fetal life through puberty, as well as studies of the hormonal and genetic effects on growth, bone maturation, puberty, sex determination and differentiation (and their disorders) and disease-causing pathology.