Mengla dianlovirus (MLAV, also written Měnglà virus) is a type of filovirus identified in a Rousettus bat in Mengla County, Yunnan Province, China, and was first reported in January 2019.
[1] The name derives from 滇 (diān), the Chinese language abbreviation for Yunnan, added to "filovirus", the common name for Filoviridae.
[1] Neither the species nor the genus are listed in the 2018 ICTV classification, as the virus was formally described after that report was released.
[4] MLAV proteins, including VP35 and VP40, inhibit host immune responses by interfering with interferon signaling, contributing to immune evasion similar to other filoviruses.
[5] Like other filoviruses, Mengla virus utilizes the Niemann-Pick C1 (NPC1) receptor for cell entry, a trait that may facilitate cross-species transmission.