MUSE, located on Mercer's main campus in Macon, Georgia, offers 10 different engineering-related majors and enrolls approximately 650 students.

In addition, in 2007 Mercer dedicated a new $14 million Science and Engineering Building adjacent to the existing school.

The new building provides additional laboratory and classroom facilities for MUSE and for science programs offered by Mercer's College of Liberal Arts.

In addition, the school's National Engineering Advisory Board, composed of some of the nation's most respected corporate leaders including Northrop Grumman, Lockheed Martin, Raytheon, Boeing, and Georgia Pacific, provides premier research and career opportunities for students.

MUSE and Robins Air Force Base maintain an educational partnership that provides on-base internships and other learning opportunities for aerospace engineering students.