Mereb was born in 1983 in Arareb, in the former province of Sahel (now part of the Northern Red Sea Region).
She is the daughter of Estifanos Derar and Negesti Wolde-Mariam, both of whom were Eritrean People's Liberation Front militants.
[1] After some initial hesitation, including trying to figure out if he was conning her, Mereb signed the contract to appear in the film.
She described her ideal role as that of a lover, though she usually played the part of a popular girl, and she cited Helen Meles as an influence.
She has performed in several other popular films, including Werasi Kidan, Gezie, Mezgeb, Shalom, Azmarino, Ketali Sehbet, and Fekri Tsa’iru.