[citation needed] Salenger resumed her acting career upon her return to Hollywood with credits including Lake Placid and The Third Wheel.

She also recorded a song titled "Flow Through Me" with Koishii and Hush; and she appeared as a background member of the Counting Crows video for "Hanging Around".

Salenger had a cameo in the Disney film Race to Witch Mountain in 2009, where she played a television reporter named Natalie Gann.

In addition, Salenger voiced a Nightsister ghost in a season three episode of Star Wars Rebels.

In November 2024, it was announced that Salenger and her husband Patton Oswalt would produce the short film Sardinia.