US 31 formerly ran along North Meridian Street for much of its length in the city of Indianapolis, before being re-routed to a segment of Interstate 465.

Nevertheless, in the early 1920s the portion of the street from Fall Creek to the canal was transferred to the parks board and a 25-foot (7.6 m) setback for new construction was imposed.

[1] In conjunction with the original proposal, an unsuccessful attempt was made to change the name of the street to Lincoln Boulevard in order to honor Abraham Lincoln in the same way that Washington Street honored George Washington.

[3] The North Meridian Street Historic District is among the most affluent urban neighborhoods in the U.S., with a mean household income of $102,599 in 2017.

[4] North of Indianapolis, Meridian Street continues into the suburbs of Carmel and Westfield.