Meriwether Smith (1730 – January 25, 1790) was an American planter from Essex County, Virginia.
He was a vocal opponent of the 1765 Stamp Act, and a representative in the revolutionary conventions that replaced the burgesses in 1775 and 1776.
In 1788, he was a member of the Virginia convention that ratified the U.S. Constitution; an Anti-Federalist, he voted against ratification.
His son by Alice was George William Smith who was Governor of Virginia from part of 1811.
Meriwether died in Essex County in January 1790, and was buried in a family plot on his plantation, "Bathurst."