In early 1898,[3][4][5] citizens in the Mesa area petitioned for and voted to establish a high school district.

During basketball games, spectators sat in the balcony (above the freshman section) or on the stage because the gym was not wide enough for sideline bleachers.

[8] In September 1932, a football player, named Zedo Ishikawa, was accidentally killed with a shotgun blast to the chest while attempting to break up a fight between two dogs.

Then, on Sunday night, October 1, 1967, a disastrous fire started in the science lab, completely destroying the sixty-year-old "Old Main.

"[12] Classes continued to graduate from the old campus until 1972 when the new Mesa High was built, at a different location (farther east and south).

Robles finished fourth at the 2009 NCAA Division I Championships at 125 pounds, seventh at the 2010 tournament, and was national champion in 2011.

The only two-time state champion siblings that both recorded undefeated seasons; twice in their high school career, (2009–2012), on the top ten wrestler list from Arizona.

[citation needed][16] *The Arizona Interscholastic Association recognized these sports and the regular season games thereof as official during these years but did not conduct playoffs to determine AIA state champions for them until 1959 for football and 1983 for soccer.