Mesokristensenia is an extinct genus of moth in the family Mesokristenseniidae.

It was named by Huang Diying, André Nel and Joël Minet in 2010, and the type species is Mesokristensenia latipenna.

The species were recovered from the Middle Jurassic Jiulongshan Formations Daohugou beds in Inner Mongolia).

Mesokristenseniidae was suggested to possibly represent a sister group to Micropterigidae.

Mesokristensenia differs from all extant Lepidoptera, except Agathiphaga, in that the forewings retain four median veins, a character shared with the lepidopteran sister order Trichoptera.