Created by Scott Connelly, an anesthesiologist, the original MET-Rx product was intended to help prevent critically ill patients from losing muscle mass.
As the product grew more popular, it was released as one formula combining the "base" and "plus" while removing the micellar casein component.
As a result, the original METAMYOSYN blend is no longer used in MET-Rx products, as the current ingredients does not contain micellar casein.
[5] In February 1995, the Penn State Sports Medicine Newsletter (3;6) published a report titled "Is It Real or Is It Met-Rx?"
that concluded, "MET-Rx ... claims of fat loss and increased muscle mass have not been proven by scientifically accepted methods."
Bridget Fonda as Melanie Ralston in Quinten Tarentino's - Jackie Brown (1997) offers Robert DeNiro's Character a Met-Rx in the kitchen scene.