Primarily designed to help adult learners, active-duty soldiers and their family members, veterans, and untraditional students, MU offers 24 different programs and certificates:[31] The Methodist University College of Medicine is home to the Cape Fear Valley Health School of Medicine, which is currently an applicant school with the Liaison Committee on Medical Education (LCME).

On February 27, 2023, a formal announcement was made by Methodist University President Stanley T. Wearden and Cape Fear Valley Health CEO Michael Nagowski of a partnership designed to create the medical school.

Pending receipt of preliminary accreditation by the LCME and approval for substantive changes by SACSCOC, the school (to be physically positioned on the campus of Cape Fear Valley Medical Center in Fayetteville, N.C.) plans to begin recruitment of an inaugural class of 80 students.

Men's sports include baseball, basketball, cheer, cross country, football, golf, lacrosse, soccer, tennis, and indoor/outdoor track and field.

Women's sports include basketball, cheer, cross country, golf, lacrosse, soccer, softball, tennis, indoor/outdoor track and field, and volleyball.