The Metro Suburban Conference (MSC) was an organization of four high schools in northern Illinois, representing seven communities in that part of the state.
[1] Glenbard South High School was added for 2010–11 following the dissolution of the Western Sun Conference.
[2] During the 2013-2014, seven former members of the Suburban Christian Conference decided to move to the MSC, effective during the 2014-2015 academic year.
Starting in 2019-20, Westmont left the Interstate Eight Conference to join the MSC following with the departure of Fenton High School.
In 2020, Guerin College Preparatory High School permanently closed due to declining enrollment, need in financial aid for students, and lower fundraising.