The conference participates in athletics and activities in the Illinois High School Association (IHSA).
The conference comprises public high schools with large enrollments, as well a private school, in the Illinois Quad Cities, Galesburg, Illinois, and Quincy, Illinois.
Sources:IHSA Conferences[4] and IHSA Member Schools Directory[5] The Western Big 6 Conference was established in 1969.
The conference consisted of four schools from the Quad Cities area, one from Quincy, and one from Galesburg.
Enrollments have ranged from over 2000 students, to Alleman, the league's only private school, with about 300.