The Metropolitan Cathedral of Saint Sebastian (Spanish: Catedral Metropolitana San Sebastián) is the cathedral of the Roman Catholic Church in the Archdiocese of Cochabamba.

It is located in the Plaza 14 de Septiembre in Cochabamba, Bolivia.

In September 2012, the cathedral was declared a National Heritage Site by the Senate of Bolivia.

[4] The cathedral's facade is a fusion of Spanish baroque and indigenous Bolivian styles.

The structure itself is built of stone and adobe masonry, with the domes and vaults made with brick and lime mortar, ornamented with ceramic tiling.