For eight decades it remained in constant use from opera house to movie theater, to a ballroom, a sports venue, a mechanic training center, and a church.

The building, by then in serious disrepair, was unused and vacant for almost eight years from 1988 until 1995, when it became the "Holy Ghost Headquarters Revival Center at the Met".

The cast included Maria Labia in the title role, Charles Dalmorès as Don José, Andrés de Segurola as Escamillo, Alice Zeppilli as Micaëla, and Cleofonte Campanini conducting.

The Met, which had annually toured to Philadelphia with performances at the Academy of Music, had been the POC's biggest competition for opera audiences.

The Metropolitan Opera's last performance at the MOH was Eugene Onegin on April 20, 1920, with Giuseppe de Luca in the title role and Claudia Muzio as Tatyana.

In April 1922, J.F Rutherford gave the first radio broadcast from the Metropolitan Opera House to an estimated 50,000 people on the discourse "Millions Now Living Will never Die".

On July 14, 1939, a crowd of 6,000 supporters, including 200 active members of the Philadelphia Police Department with German Nazi sympathies, filled the Met to hear the radical anti-Jewish preacher Father Charles Coughlin commission John F. Cassidy to lead his new pro-fascist Christian Front organization.

[11] In the late 1930s, the MOH became a ballroom and in the 1940s a sports promoter bought the venue, covered the orchestra pit with flooring so basketball, wrestling, and boxing could take place.

[17] In February 2015, the church filed a lawsuit against the developer over the lack of progress on the building, alleging that Blumenfeld misled the congregation regarding his finances and "...never restored the Met as promised.

[18][19] With restoration work led by Atkin Olshin Schade Architects and Domus as the general contractor, the completely renovated Met Philadelphia reopened to the public on December 3, 2018, with a Bob Dylan concert.

[20] One year later Sirius XM radio hosted at the Met the smallest Phish performance in two decades on December 3, 2019.