Mettupalayam is situated at the base of Nilgiri Hills and hence is the starting point for the Ghat Roads.

MEMU express special trains are operated between Coimbatore Junction and Mettupalayam daily.

There is a proposal for a bypass road from Sulur (Kangayampalayam) via Neelambur for Mettupalayam via Odanthurai to Ooty.

National Highway 181 (India) connecting Gundlupet in Karnataka state to Nagapattinam passes through Mettupalyam.

State highway SH15 from Erode to Ooty passes through Chithode, Gobichettipalayam, Sathyamangalam, Sirumugai, Mettupalayam and Kotagiri.