[5][6] The debut demo EP by mewithoutYou, Blood Enough For Us All, was released in 2000, the year before the band was officially founded.

[8] Over the next year, the band signed to Tooth & Nail Records and released their debut album, [A→B] Life.

[10] Brother, Sister, mewithoutYou's third album (released in 2006), was moved away from the emo and hardcore punk influences of their earlier work and featured less abrasive vocals by Aaron Weiss.

It's Alright in 2009, the band shifted genres entirely, recording an album that is almost entirely acoustic and has been compared to "campfire songs".

[19] Due to the COVID-19 pandemic, mewithoutYou postponed their final tour until 2022 and played their last concert on August 20, 2022, in Philadelphia.