[clarification needed] The first segment runs westward from Zapotlanejo, Jalisco eastward to Irapuato, Guanajuato and connects to Guadalajara via Mexican Federal Highway 80.

[4] The total length of the highway segment is 217.6 km (135.2 mi).

The total length of the highway segment is 118.1 km (73.4 mi).

[7][8] The highway is under the management of the Secretariat of Communications and Transportation of Mexico and custody is under the responsibility of "The Federal Road Police" (a part of the Federal Preventive Police, PFP).

The road connects the following cities from west to east: Zapotlanejo, Ocotlán, Degollado, La Piedad, Pénjamo, Abasolo, and Irapuato.