Mezquital is a municipality in the Mexican state of Durango.

The municipal seat lies at San Francisco del Mezquital.

The municipality covers an area of 7,196.5 km².

[2] The municipality had 1,325 localities, the largest of which (with 2010 population in parentheses) was: San Francisco del Mezquital (1,742), classified as urban.

[1] This article about a location in the Mexican state of Durango is a stub.