Mfantsiman Girls' Senior High School[1] is an all-girls second cycle institution in Saltpond in the Central Region of Ghana.

The aim was to equip them with essential skills that would enable them to harness their potential and contribute productively to society.

This initiative aimed to facilitate poverty alleviation, foster socio-economic growth, and contribute to the overall development of the nation.

The school's motto is 'Obra Nye Woara abo' in Twi meaning 'Life is what you make it'.

In terms of student accommodations, the girls are allocated to seven distinct residences, namely Mfantsiman Girls enjoy a strong partnership with the male students of Adisadel College, collectively referred to as SANTAMOGA.