Mi Zhu (c. 165–221),[1] courtesy name Zizhong, was a Chinese military general and politician who served under the warlord Liu Bei in the late Eastern Han dynasty, during the Three Kingdoms period, after Liu Bei founded the state of Shu Han.

Nonetheless, Mi along with Jian Yong, Sun Qian, and later Yi Ji, greatly contributed to the Liu's populist movement to restore the Han dynasty through literature and essays.

Mi Zhu was born in Qu County (朐縣), Donghai Commandery (東海郡), which is present-day Lianyungang, Jiangsu.

[2] According to In Search of the Supernatural (搜神記) by Gan Bao (干竇), a work largely consisting of legends and hearsays, Mi Zhu was once returning home from the capital Luoyang when he met a lady by the road.

Cao Cao had once attempted to entice Mi Zhu and Mi Fang to serve him by offering them governorships of Ying Commandery (northwest of present-day Laiwu, Shandong) and Pengcheng Commandery respectively but was turned down, and the brothers fled with Liu Bei.

The Lieutenant-General (偏將軍), Mi Zhu is naturally faithful and loyal and is reliable to command military and civil affairs; Hence I request to have him take office as Administrator of Yíng Commandery (嬴郡太守), to comfort the officials and people.”[8] When Liu Bei sought refuge with Liu Biao, he sent Mi Zhu first to meet and discuss with him.

After Liu Bei conquered Yi Province (covering present-day Sichuan and Chongqing) in 214, Mi Zhu was promoted to General Who Pacifies Han (安漢將軍).

[9] Although Mi Zhu was known for his kindness and his grace; he was not given any troops to command, as military manoeuver were not his expertise, he was nonetheless the most highly esteemed among Liu Bei's subjects.

When he heard of this, Mi Zhu bound himself and came to Liu Bei, pleading guilty for his brother's crime.