Cresap, believing the rumors, was apparently involved in a reprisal raid, and he or some of his followers killed two or three mingo in the vicinity of Captina Creek, in present day Ohio.
As a result of the murders, Logan waged war on the settlements along the Ohio and in western Pennsylvania, killing, perhaps, nearly thirty men, women and children.
Lord Dunmore, the Governor of Virginia, raised an army and appointed Cresap to the rank of Captain.
After Lord Dunmore's War, Cresap returned to Maryland and subsequently raised a company of riflemen for the Continental Army during the American Revolution.
He died from illness in New York City while in the service of the army; he is interred there in Trinity Church Cemetery.