Painters Georgios Klontzas and Damaskenos were major contributors to the Cretan School during the same period.

He remained loyal to his Greek roots stylistically but incorporated some Italian elements in his work.

According to legend, Damaskinos spent some time living and working in Vrontisi Monastery, where six of his icons were kept until 1800.

He painted icons for the Greek Orthodox Cathedral of San Giorgio dei Greci in Venice.

[7] His only daughter Antonia married painter Ioannis Mavrikas-Mandouphos or Yannas Mantoufos.

[8] Extensive work was later completed at the church San Giorgio dei Greci by famous painter Emmanuel Tzane-Bounialis.

He used a particular rose color that characterized his paintings, his figure dimensions were defined by only a few brush strokes.

[11] Damaskinos was also the first artist to introduce paler flesh tones to post-Byzantine painting and it was one of the stylistic features of his work which proved highly influential from the second half of the sixteenth century and onwards.

Damaskinos completed works for the church San Giorgio dei Greci between 1560 and 1583.

The dodekaorto also known as the Great feasts in the Eastern Orthodox Church is featured in nine of the paintings.