Michael O'Donohue (1835 – December 19, 1912) was an Irish-American builder and architect from Hartford, Connecticut who designed a number of ecclesiastical buildings in New England for both Roman Catholic and Jewish clients.

He carried on an active business as a designer of Catholic churches in the Gothic Revival style.

O'Donohue is one of the few architects of Catholic churches to have also built for non-Catholic clients as well.

[1] O'Donohue is not as significant a figure in 19th century American Catholic architecture as his fellow countrymen and contemporaries Patrick.

[citation needed] Nonetheless his work is appreciated today and several of his buildings have been selected to National Registers.