He was selected by the Denver Broncos in the third round of the 2014 NFL draft and was on their Super Bowl 50 championship team.

He has also played in the NFL for the Los Angeles Chargers, Carolina Panthers, Chicago Bears, Baltimore Ravens and the Detroit Lions.

[1][2] Schofield liked baseball as a youth, but tagged along with his younger brother, Andrew, who liked to play football.

[5][6] Sources: Schofield earned 2013 All-Big Ten Conference honorable mention recognition from the coaches.

[7] He excelled in the pre 2014 Senior Bowl workouts earning NFL Network player of the day on Wednesday January 22.

[12] On February 7, 2016, Schofield was a starter on the Broncos Super Bowl 50 championship team that beat the Carolina Panthers by a score of 24–10.

[19] On May 2, 2020, Schofield signed with the Carolina Panthers,[20] where he was reunited with former Broncos and Chargers offensive line teammate Russell Okung under former Chargers offensive line coach Pat Meyer, who held the same position with the Panthers.

[30] Schofield made his first start of the season at left guard in a week 7 victory over the New England Patriots on Monday Night Football.

[36][37] They both attended the same high school in Orland Park, but didn't start to date until they were both college-age athletes and met at a local gym.

On March 1, 2021, the Chicago Red Stars of the National Women's Soccer League announced that Schofield and his spouse Kendall Coyne Schofield had joined the women's soccer team's ownership group.

A portion of the park redevelopment was renamed to the "Michael Schofield III Sports Complex" in recognition of the foundation's funding.