Michael Spinks vs. Larry Holmes II, billed as Vindication in Vegas, was a professional boxing match contested on 19 April 1986, IBF, The Ring and Lineal heavyweight championship.

[3] In October 1985, shortly after Michael Spinks defeated Larry Holmes to win the heavyweight title, promotor Don King pitched to HBO Sports president Seth Abraham a World Series style competition to unify the heavyweight division which had been without an undisputed champion since Leon Spinks in 1978.

By mid January 1986 negotiations between King and the other promoters (including Spinks' promoter Butch Lewis) were completed and the Heavyweight unification series was set to began in March with Pinklon Thomas vs. Trevor Berbick.

Holmes would start the fight strong, throwing many hard shots and left jabs while Spinks was focused on dodging punches and keeping out of range.

Speaking in the ring afterwards Spinks said "I had to stay cool and calm, then break his morale, Larry proved to be one hell of a champion.