His works comment on topical issues in Malawi and reflect the social and political realities of Malawian life.

In 2010 he made an appearance at the MWA (Malawi Washington Association) Extravaganza 2010 Panel discussion hosted by the MWA at the Malawian Embassy in Washington DC where he discussed the history of the Malawian Film industry and his ideas on its expansion.

On 6 February 2019, United Transformation Movement (UTM) leader Saulos Klaus Chilima unveiled Michael Usi as his running mate for May 21 tripartite elections.

On 8 July 2020, Michael Usi was appointed Minister of Tourism, Wildlife and Culture of the Republic of Malawi in the cabinet of President Lazarus Chakwera.

[7] On 20 June 2024, Usi was appointed as vice president of Malawi following the death of his predecessor Saulos Chilima in a plane crash.