Onyenwere finished her college career fourth on UCLA's all-time scoring list with 1,888-career points.

With the Liberty acquiring star frontcourt players such as Breanna Stewart and Jonquel Jones before the 2023 season, Onyenwere's roster spot was in question and she was consequently traded.

[8] She started 27 of 40 games and set career highs in every category, but it was a disappointing season for the Mercury, who finished 12th in the league with a 9–31 record.

[10] Onyenwere saw limited playing time in the first half of the 2024 season, but earned a place in the starting lineup after the Olympic break, replacing Marina Mabrey, who was traded to the Connecticut Sun.

[13] In December 2021, Onyenwere joined the Catalan team Uni Girona CB of the Spanish Liga Femenina de Baloncesto.

[17] In February 2025, Onyenwere joined the Jiangsu Phoenix of the Women's Chinese Basketball Association (WCBA).