[2] As of 2016, Ogwumike was elected vice-president of the WNBA Players Association, and signed an endorsement deal with Adidas.

[7] She participated in the 2010 WBCA High School All-America Game, where she scored 24 points,[8] and earned MVP honors for the White team.

[citation needed] After the WNBA season ended, Ogwumike signed with Italian club Famila Schio.

[20] In April 2017, Ogwumike was suspended by the Sun for the entire 2017 season to free up a roster spot due to her injury and that same month she also signed a contract extension.

[21] On May 20, 2018, Ogwumike made her return to the Sun in their season debut, playing her first WNBA game in two years.

[25] The Sun finished as the number 4 seed in the league with a 21–13 record, receiving a bye to the second round elimination game.

On April 28, 2019, Ogwumike was traded to the Los Angeles Sparks for a 2020 first-round pick, reuniting her with her sister Nneka.

In June 2020, Ogwumike announced she would sit out the 2020 WNBA season due to health concerns of playing in the bubble during the COVID-19 pandemic.

In August 2020, she became the first Black woman to host a national radio show for ESPN, while also becoming the first WNBA player to do so as well.

She is one of the youngest commentators to be named a full-time NBA analyst for ESPN, while simultaneously playing in the WNBA.

[39] In December 2020, Ogwumike was named to Forbes 30 Under 30, alongside fellow WNBA players, Natasha Cloud and A'ja Wilson.

[41] In October 2023, Ogwumike became an inaugural member of the President's Advisory Council on African Diaspora Engagement in the United States.