Michel-Siméon Delisle (September 27, 1856 – October 11, 1931) was a Canadian merchant and politician.

Born in Pointe-aux-Trembles, Portneuf County, Canada East, the son of Albert Delisle and Dina Bertrand, Delisle was educated in Quebec City.

A Liberal, he served for almost 30 years for the riding of Portneuf.

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