In 2021 he competed in the Supersport World Championship aboard a Kawasaki ZX-6R, before retiring on September 26 from motorsport as a sign of protest after Dean Berta Viñales fatal crash in Jerez.

[1] Despite his lack of experience and riding with inferior equipment compared to his racing rivals, Fabrizio managed to impress the paddock with several point scoring finishes and by consistently outpacing his teammate, Chris Burns.

During the Dutch grand prix at Assen, Fabrizio fractured his ankle in a spectacular crash, forcing him to miss the next round in Brazil.

Regular rider Shane Byrne was suffering from a broken wrist, leading Aprilia to fly both Fabrizio and Anthony West out to Mugello to test the bike alongside Jeremy McWilliams.

[3] Realizing his dream of riding for a factory team ended up becoming an unravelling for Fabrizio, as he suffered a violent headshake from the much-maligned RS Cube during the first lap of the race.

[4][5] With expectations to return to the Harris WCM team for the next round at Motegi in Japan,[5] he suddenly found himself without a ride, being replaced by 125cc rider Youichi Ui.

To end his 2004 season, he took a ride with Team Italia Megabike in the Supersport World Championship, competing in the final two rounds of the series.

At Brno in the 2006 Superbike World Championship, he started tenth, but chose hard-compound tyres, which remained on the pace as other riders faded.

In the first race he passed a fading Andrew Pitt as well as Fonsi Nieto, Troy Corser and Noriyuki Haga in the closing laps to score his first Superbike World Championship podium finish.

As Corser attempted a move, Fabrizio dived down the inside of both, slithering and nearly hitting Haga, before edging ahead of them both to the line, immediately improving on his career-best result with a second.