Michele Di Ruberto (born 28 August 1934) is an Italian prelate of the Roman Catholic Church.
Di Ruberto was born in Pietra Montecorvino, and was ordained to the priesthood on 29 September 1957.
In 1984, Di Ruberto was placed in charge of verifying miracles attributed to candidates for canonization, and in 1993 was named the Congregation's Undersecretary.
On 5 May 2007, he was appointed Secretary of Causes of Saints and Titular Archbishop of Biccari by Pope Benedict XVI.
He received his episcopal consecration on the following 30 June from Cardinal Secretary of State Tarcisio Bertone, SDB, with Cardinal José Saraiva Martins and Bishop Francesco Zerrillo serving as co-consecrators.